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Biomarkers of exposure assessment : ウィキペディア英語版 | Biomarkers of exposure assessment
Biomarkers are very useful in the world of exposure assessment when dealing with direct measurement methods. The use of biomarkers in exposure studies is also referred to as biomonitoring. They are chemicals, metabolites, susceptibility characteristics, or changes in the body that relate to the exposure of an organism to a chemical. Biomarkers have the ability to identify if an exposure has occurred, the route of exposure, the pathway of exposure, or the resulting effects of the exposure. When dealing with exposure assessment, there are three types of biomarkers that can be useful, biomarkers of susceptibility, biomarkers of exposure, and biomarkers of effect. ==Biomarkers of susceptibility== Biomarkers of susceptibility are indicators of the natural characteristics of an organism that make it more susceptible to the effects of an exposure to a chemical. They can help define what sensitivities are more susceptible as well as critical times when exposures can be most detrimental. For example, the exhalation strength of an asthmatic will indicate how susceptible that person would be to the respiratory effects of exposure to brevetoxin, the toxic compound produced during a red tide.
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